Estimation of Glomerular Filtration Rate: An Update

Reprinted for our readers interest originally published PJKD 2018;2(4):38-42.

Autors/ores

  • Salman Tahir Shafi Fatima Memorial Hospital, Lahore.

DOI:

https://doi.org/10.53778/pjkd35112

Paraules clau:

glomerulofiltration rate, CKD-EPI, MDRD, cockcroft and Gault, creatinine clearance, inulin clearance, estimated glomerulofiltration rate, chronic kidney disease, CKD

Resum

 

Glomerular filtration rate (GFR) estimation is the fundamental component of assessment of renal function. Kidney disease: Improving global outcomes (KDIGO) guidelines define chronic kidney disease (CKD) as decline in GFR of <60 ml/min/1.73m2 or presence of kidney damage for 3 or more months 1. GFR can be measured indirectly as the clearance of exogenous filtration markers that are eliminated by the kidney only by glomerular filtration i-e Inulin, Iothalamate, Iohexol, 51Cr-EDTA or 99mTC-DTPA. In routine clinical practice, GFR is assessed from serum concentrations of endogenous filtration markers like Urea, creatinine or Cystatin C.

This review will discuss the different aspects of estimation of GFR and its implications.

PJKD

Descàrregues

Publicat

2021-02-07

Número

Vol. 3 Núm. 5 (2019): Pakistan Journal of Kidney Diseases

Secció

Review Article

Llicència

Drets d'autor (c) 2021 Salman Tahir Shafi

Creative Commons License

Aquesta obra està sota una llicència internacional Creative Commons Reconeixement-NoComercial 4.0.

Com citar

Estimation of Glomerular Filtration Rate: An Update: Reprinted for our readers interest originally published PJKD 2018;2(4):38-42. (2021). Pakistan Journal of Kidney Diseases, 3(5). https://doi.org/10.53778/pjkd35112