Estimation of Glomerular Filtration Rate: An Update

Reprinted for our readers interest originally published PJKD 2018;2(4):38-42.

Auteur/ices

  • Salman Tahir Shafi Fatima Memorial Hospital, Lahore.

DOI :

https://doi.org/10.53778/pjkd35112

Mots-clés :

glomerulofiltration rate, CKD-EPI, MDRD, cockcroft and Gault, creatinine clearance, inulin clearance, estimated glomerulofiltration rate, chronic kidney disease, CKD

Résumé

 

Glomerular filtration rate (GFR) estimation is the fundamental component of assessment of renal function. Kidney disease: Improving global outcomes (KDIGO) guidelines define chronic kidney disease (CKD) as decline in GFR of <60 ml/min/1.73m2 or presence of kidney damage for 3 or more months 1. GFR can be measured indirectly as the clearance of exogenous filtration markers that are eliminated by the kidney only by glomerular filtration i-e Inulin, Iothalamate, Iohexol, 51Cr-EDTA or 99mTC-DTPA. In routine clinical practice, GFR is assessed from serum concentrations of endogenous filtration markers like Urea, creatinine or Cystatin C.

This review will discuss the different aspects of estimation of GFR and its implications.

PJKD

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Publiée

2021-02-07

Numéro

Vol. 3 No 5 (2019): Pakistan Journal of Kidney Diseases

Rubrique

Review Article

Licence

Merci de créditer les auteurs lors de toute citation : Salman Tahir Shafi (2021)

Creative Commons License

Ce travail est disponible sous licence Creative Commons Attribution - Pas d’Utilisation Commerciale 4.0 International.

Comment citer

Estimation of Glomerular Filtration Rate: An Update: Reprinted for our readers interest originally published PJKD 2018;2(4):38-42. (2021). Pakistan Journal of Kidney Diseases, 3(5). https://doi.org/10.53778/pjkd35112