Estimation of Glomerular Filtration Rate: An Update

Reprinted for our readers interest originally published PJKD 2018;2(4):38-42.

Các tác giả

  • Salman Tahir Shafi Fatima Memorial Hospital, Lahore.

DOI:

https://doi.org/10.53778/pjkd35112

Từ khóa:

glomerulofiltration rate, CKD-EPI, MDRD, cockcroft and Gault, creatinine clearance, inulin clearance, estimated glomerulofiltration rate, chronic kidney disease, CKD

Tóm tắt

 

Glomerular filtration rate (GFR) estimation is the fundamental component of assessment of renal function. Kidney disease: Improving global outcomes (KDIGO) guidelines define chronic kidney disease (CKD) as decline in GFR of <60 ml/min/1.73m2 or presence of kidney damage for 3 or more months 1. GFR can be measured indirectly as the clearance of exogenous filtration markers that are eliminated by the kidney only by glomerular filtration i-e Inulin, Iothalamate, Iohexol, 51Cr-EDTA or 99mTC-DTPA. In routine clinical practice, GFR is assessed from serum concentrations of endogenous filtration markers like Urea, creatinine or Cystatin C.

This review will discuss the different aspects of estimation of GFR and its implications.

PJKD

Lượt tải xuống

Đã Xuất bản

2021-02-07

Số

Tập 3 Số 5 (2019): Pakistan Journal of Kidney Diseases

Chuyên mục

Review Article

Giấy phép

Bản quyền (c) {copyrightHolder}

Creative Commons License

Tác phẩm này được cấp phép theo Giấy phép Creative Commons Ghi công-Phi thương mại 4.0 Quốc tế.

Cách trích dẫn

Estimation of Glomerular Filtration Rate: An Update: Reprinted for our readers interest originally published PJKD 2018;2(4):38-42. (2021). Pakistan Journal of Kidney Diseases, 3(5). https://doi.org/10.53778/pjkd35112