Update on Treatment and Prevention of Chronic Antibody Mediated Rejection in Renal Transplant Recipients

Các tác giả

  • Salman Tahir Shafi Sharif Medical and Dental College, Lahore

DOI:

https://doi.org/10.53778/pjkd40353

Từ khóa:

Rejection, kidney transplant, acute rejection, chronic rejection, antibody mediated rejection, complement,, plasmapheresis, Bortezomib,, Rituximab, Eculizumab, Tocilizumab

Tóm tắt

Chronic antibody mediated rejection (AMR) is a major cause of allograft failure1,2. Chronic AMR clinically presents with proteinuria and gradual decline in renal function. The underlying mechanisms of AMR include both antibody mediated complement-dependent cytotoxicity, complement-independent cellular cytotoxicity and other mechanisms. The purpose of this review is to appraise recent literature on diagnosis, treatment and prevention of chronic AMR.

PJKD

Lượt tải xuống

Đã Xuất bản

2021-01-31

Số

Tập 4 Số 03 (2020): Pakistan Journal of Kidney Diseases

Chuyên mục

Review Article

Giấy phép

Bản quyền (c) {copyrightHolder}

Creative Commons License

Tác phẩm này được cấp phép theo Giấy phép Creative Commons Ghi công-Phi thương mại 4.0 Quốc tế.

Cách trích dẫn

Update on Treatment and Prevention of Chronic Antibody Mediated Rejection in Renal Transplant Recipients. (2021). Pakistan Journal of Kidney Diseases, 4(03). https://doi.org/10.53778/pjkd40353